Sage

A blazing-fast proteomics search engine — database search, quantification, FDR control, and RT prediction, all in one tool.

DocumentationCI / BenchmarksGitHub
Fast
Fragment-index search, Rayon-parallel across all cores.
Searches billions of spectra. Open-search with >500 Da precursor tolerance in minutes, not hours.
End-to-end
One tool, no pipeline glue.
Search, LFQ & TMT quantification, RT prediction, LDA rescoring, FDR control, picked-protein approach.
Cloud-ready
Stream mzML straight from S3.
Runs just as well on your laptop. Cross-platform binaries on every release.